AHK-Cu (Alanyl-Histidyl-Lysine Copper Complex)

1. Basic Overview

2. Mechanism of Action

1. Stimulate proliferation of dermal papilla cells (DPCs), inhibit DPC apoptosis, extend hair follicle anagen (growth) phase.
2. Upregulate VEGF and SCF expression, boost microvascular angiogenesis around follicles to improve nutrient supply.
3. Promote fibroblast activity and Type I collagen synthesis, support dermis reconstruction and anti-fibrosis research.
4. Deliver bioavailable copper ions as essential enzyme cofactor; moderate oxidative stress and relieve local inflammation.
5. Activate Wnt/β-catenin signaling pathway critical for follicle regeneration.

3. Primary Observed Research Effects

• Activate dormant hair follicles, counteract follicle miniaturization
• Improve hair density and hair shaft thickness in preclinical models
• Accelerate skin tissue repair and wound closure
• Boost collagen synthesis, investigate anti-aging skin remodeling
• Reduce inflammatory response in epidermal tissue models

4. Reconstitution Instructions (Lyophilized Powder)

1. Let the peptide vial warm to room temperature first. Sterilize rubber stopper with alcohol wipe.
2. Slowly inject Bacteriostatic Water (BAC water) along the inner wall of the vial, avoid direct impact on lyophilized powder.

Recommended concentration: Mix 10mg powder with 2mL BAC water → 5mg/mL working solution.

3. Gently swirl/roll the vial to dissolve powder. DO NOT shake violently to prevent peptide denaturation. Fully dissolved solution displays characteristic light blue color.
4. Storage Rules

• Unreconstituted lyophilized powder: Store at -20°C, sealed and protected from light. Shelf life up to 24 months.
• Reconstituted solution: Refrigerate 2–8°C, stable within 28 days. Avoid repeated freeze-thaw cycles and light exposure.

5. Research Administration Protocols

Option 1: Subcutaneous Injection (Localized Research)

• Reference Dosage: 100 mcg – 300 mcg per injection
• Frequency: 3–5 times weekly
• Injection Site: Abdominal subcutaneous tissue or target scalp region
• Cycle Reference: 8–12 weeks experimental cycle, followed by equal rest period

Option 2: Topical Application (Dermatology & Hair Research)

• Working concentration range: 0.1 mg/mL ~ 2 mg/mL
• Application: Apply evenly to target tissue area, once or twice daily for experimental observation

Note: Topical penetration is weaker than local injection in research comparisons.

6. Precautions

1. Purely laboratory research reagent. Not approved for human medical use.
2. Copper peptide is sensitive to oxidation. Avoid long-term exposure under light.
3. Strict sterile operation required during reconstitution to prevent contamination.
4. Cease experiment immediately if precipitation, turbidity or abnormal irritation occurs.

Short Version (For Product Page / Customer Direct Message)

AHK-Cu Peptide

Reconstitution

Reference Research Dosage (Subcutaneous)